Since starting Custom Choice Cereal for a gluten-intolerant friend in 2009 there has rarely been a day where I didn't learn something new about celiac disease. However, I am again and again amazed by how little is known about the triggers for celiac disease and why exactly it is on the rise, as research by Dr. Alessio Fasano from the University of Maryland's Center for Celiac Research indicates.
I also like to stress that unlike many other conditions, a strict adherence to a gluten-free diet is an (the only!) effective treatment for the autoimmune disease. While that sounds stressful and can initially be overwhelming we like to look at the bright side of things: absolutely no medication is needed!
Researchers from the University of Chicago's Celiac Disease Center used mice to identify a biochemical interaction that may trigger an autoimmune reaction in the intestines of genetically susceptible people. Specifically, they found that the compound retinoic acid in combination with high levels of the a pro-inflammatory substance known as interleukin-15 was able to break the body's tolerance to gluten.
